How Mounjaro works
- Tirzepatide acts on two hormone receptors involved in blood glucose regulation and appetite control.
- These actions can help improve glycaemic control and support reduced calorie intake as part of a wider treatment plan.
Prescribing and suitability
- Mounjaro is not suitable for everyone.
- Supply is subject to a clinical consultation assessing medical history, current medications, and individual risk factors.
- Dosing usually starts at a low dose and is increased gradually, depending on tolerance and clinical response.
- Dose changes are made only under prescriber guidance.
Possible side effects
- As with all medicines, side effects can occur.
- Commonly reported side effects include:
- Nausea
- Vomiting
- Diarrhoea
- Constipation
- Reduced appetite
- Gastrointestinal side effects are more common during dose increases and are often temporary.
- Patients should seek medical advice if side effects are severe, persistent, or concerning.
Important information
- Mounjaro may not be suitable for individuals with certain medical conditions, including some endocrine disorders or a history of pancreatitis.
- Full safety information is reviewed during the consultation process.
- Treatment should be used alongside appropriate dietary, lifestyle, and behavioural support, where advised.
Regulatory information
- Prescription-only medicine (POM)
- Supplied in accordance with UK medicines legislation
- No supply without a completed consultation and prescriber approval
- This information does not replace advice from a healthcare professional


